Vielhauer, George A.: search on Z-Library

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1

Efficacious Cyclic N -Acyl O -Amino Phenol Duocarmycin Prodrugs

Wolfe, Amanda L., Duncan, Katharine K., Parelkar, Nikhil K., Brown, Douglas, Vielhauer, George A., Boger, Dale L.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.05 MB

english, 2013

2

Modulation of JB6 mouse epidermal cell transformation response by the prostaglandin F2α receptor

Thomas J. Weber, Lye M. Markillie, William B. Chrisler, George A. Vielhauer, John W. Regan

Journal:

Molecular Carcinogenesis

Year:

2002

Language:

english

File:

PDF, 198 KB

english, 2002

3

Targeting the Heat Shock Protein 90 Dimer with Dimeric Inhibitors

Kusuma, Bhaskar Reddy, Peterson, Laura B., Zhao, Huiping, Vielhauer, George, Holzbeierlein, Jeffrey, Blagg, Brian S. J.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 4.17 MB

english, 2011

4

The hERG Channel Is Dependent upon the Hsp90α Isoform for Maturation and Trafficking

Peterson, Laura B., Eskew, Jeffrey D., Vielhauer, George A., Blagg, Brian S. J.

Journal:

Molecular Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 3.14 MB

english, 2012

5

[ECS 212th ECS Meeting - Washington, DC (October 7 - October 12, 2007)] ECS Transactions - VUV Luminescence Due to 5d - 4f Transitions in Gd3+ and Lu3+ Ions Doped into Fluoride Crystals

Makhov, Vladimir, Kirm, Marco, Stryganyuk, Gregory, Vielhauer, Sebastian, Zimmerer, Georg

Year:

2008

Language:

english

File:

PDF, 482 KB

english, 2008

6

A Novel, Unusually Efficacious Duocarmycin Carbamate Prodrug That Releases No Residual Byproduct

Wolfe, Amanda L., Duncan, Katharine K., Parelkar, Nikhil K., Weir, Scott J., Vielhauer, George A., Boger, Dale L.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 524 KB

english, 2012

7

486 DEVELOPMENT OF A HIGH-THROUGHPUT SCREENING ASSAY FOR THE IDENTIFICATION OF CANCER CELL-SPECIFIC HSP90

Woodruff, Daniel, Sadikot, Takrima, Eskew, Jeff, Blagg, Brian, Vielhauer, George, Holzbeierlein, Jeffrey

Journal:

The Journal of Urology

Year:

2012

Language:

english

File:

PDF, 50 KB

english, 2012

8

MRX 501: A novel ultrasound contrast agent with therapeutic properties

Unger, Evan C., McCreery, Tom, Sweitzer, Robert, Vielhauer, George, Wu, GuanLi, Shen, DeKang, Yellowhair, David

Journal:

Academic Radiology

Year:

1998

Language:

english

File:

PDF, 993 KB

english, 1998

9

Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors

Kusuma, Bhaskar Reddy, Khandelwal, Anuj, Gu, Wen, Brown, Douglas, Liu, Weiya, Vielhauer, George, Holzbeierlein, Jeffrey, Blagg, Brian S.J.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.58 MB

english, 2014

10

VUV luminescence of BaF2, BaF2:Nd and BaY2F8 crystals under inner-shell excitation

Marco Kirm, Aleksandr Lushchik, Cheslav Lushchik, Vladimir Makhov, Evgeni Negodin, Sebastian Vielhauer, Georg Zimmerer

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2002

Language:

english

File:

PDF, 332 KB

english, 2002

11

Biological characterization of preclinical Bioluminescent Osteosarcoma Orthotopic Mouse (BOOM) model: A multi-modality approach

Garimella, Rama, Eskew, Jeff, Bhamidi, Priyanka, Vielhauer, George, Hong, Yan, Anderson, H. Clarke, Tawfik, Ossama, Rowe, Peter

Journal:

Journal of Bone Oncology

Year:

2013

Language:

english

File:

PDF, 3.97 MB

english, 2013

12

610 IN VIVO EFFICACY OF KU-174, A C-TERMINAL INHIBITOR OF HSP90 IN A PC3 XENOGRAFT MODEL

James, Andrew, Holzbeierlein, Jeffrey, Eskew, Jeffrey, Blagg, Brian, Rajewski, Roger, Vielhauer, George

Journal:

The Journal of Urology

Year:

2011

Language:

english

File:

PDF, 41 KB

english, 2011

13

Hsp90 C-Terminal Inhibitors Exhibit Antimigratory Activity by Disrupting the Hsp90α/Aha1 Complex in PC3-MM2 Cells

Ghosh, Suman, Shinogle, Heather E., Garg, Gaurav, Vielhauer, George A., Holzbeierlein, Jeffrey M., Dobrowsky, Rick T., Blagg, Brian S. J.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 4.77 MB

english, 2015

14

Triazole containing novobiocin and biphenyl amides as Hsp90 C-terminal inhibitors

Zhao, Jinbo, Zhao, Huiping, Hall, Jessica A., Brown, Douglas, Brandes, Eileen, Bazzill, Joseph, Grogan, Patrick T., Subramanian, Chitra, Vielhauer, George, Cohen, Mark S., Blagg, Brian S. J.

Journal:

Year:

2014

Language:

english

File:

PDF, 866 KB

english, 2014

15

Vacuum ultraviolet spectroscopy of excitons in solid krypton

Kisand, Vambola, Kirm, Marco, Vielhauer, Sebastian, Zimmerer, Georg

Journal:

Journal of Physics Condensed Matter

Year:

2002

Language:

english

File:

PDF, 291 KB

english, 2002

16

Zero-phonon lines in the d → f luminescence of LiYF4 : Er3+

Yonghu Chen, Marco Kirm, Evgueni Negodin, Marcus True, Sebastian Vielhauer, Georg Zimmerer

Journal:

physica status solidi (b)

Year:

2003

Language:

english

File:

PDF, 76 KB

english, 2003

17

Uric Acid Elicits Anti-Tumor Humoral Immunity Without T Cell Expansion When Used As A Vaccine Adjuvant

Wagner, Wolfgang, Krco, Christopher, Behrens, Marshall, Vielhauer, George, Disis, Mary L, Knutson, Keith L

Journal:

Journal of Immunotherapy

Year:

2005

Language:

english

File:

PDF, 1.45 MB

english, 2005

18

Activity of Anticancer Agents in a Three-Dimensional Cell Culture Model

Nirmalanandhan, Victor Sanjit, Duren, Alicia, Hendricks, Peter, Vielhauer, George, Sittampalam, Gurusingham Sitta

Journal:

Assay and Drug Development Technologies

Year:

2010

Language:

english

File:

PDF, 535 KB

english, 2010

19

The Design, Synthesis, and Evaluation of Coumarin Ring Derivatives of the Novobiocin Scaffold that Exhibit Antiproliferative Activity

Donnelly, Alison C., Mays, Jared R., Burlison, Joseph A., Nelson, John T., Vielhauer, George, Holzbeierlein, Jeffrey, Blagg, Brian S. J.

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 677 KB

english, 2008

20

Eukaryotic initiation factor 4E variants alter the morphology, proliferation, and colony-formation properties of MDA-MB-435 cancer cells

Tovë M. Goldson, George Vielhauer, Eveline Staub, Steve Miller, Hyunsuk Shim, Curt H. Hagedorn

Journal:

Molecular Carcinogenesis

Year:

2007

Language:

english

File:

PDF, 627 KB

english, 2007

21

Cloning and localization of hFPS: a six-transmembrane mRNA splice variant of the human FP prostanoid receptor

George A Vielhauer, Hiromichi Fujino, John W Regan

Journal:

Archives of Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 744 KB

english, 2004

22

Evaluation of a reductively activated duocarmycin prodrug against murine and human solid cancers

Vielhauer, George A., Swink, Megan, Parelkar, Nikhil K., Lajiness, James P., Wolfe, Amanda L., Boger, Dale

Journal:

Cancer Biology & Therapy

Year:

2013

Language:

english

File:

PDF, 1.55 MB

english, 2013

23

Hsp90: A Drug Target?

Jeffrey M. Holzbeierlein, Andrew Windsperger, George Vielhauer

Journal:

Current Oncology Reports

Year:

2010

Language:

english

File:

PDF, 123 KB

english, 2010

24

696 CHARACTERIZATION OF A C-TERMINAL HEAT SHOCK PROTEIN 90 INHIBITOR IN PROSTATE CANCER CELLS

Penn, Heidi A., Manthe, Craig A., Comer, Shawna B., Vielhauer, George A., Rajewski, Roger J., Blagg, Brian S.J., Holzbeierlein, Jeffrey M.

Journal:

The Journal of Urology

Year:

2010

Language:

english

File:

PDF, 53 KB

english, 2010

25

Development of Novobiocin Analogues That Manifest Anti-proliferative Activity against Several Cancer Cell Lines

Burlison, Joseph A., Avila, Christopher, Vielhauer, George, Lubbers, Donna J., Holzbeierlein, Jeffrey, Blagg, Brian S. J.

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 205 KB

english, 2008

26

Creation of free excitons in solid krypton investigated by time-resolved luminescence spectroscopy

Kisand, Vambola, Kirm, Marco, Negodin, Evgeni, Sombrowski, Elke, Steeg, Barbara, Vielhauer, Sebastian, Zimmerer, Georg

Journal:

Journal of Physics Condensed Matter

Year:

2003

Language:

english

File:

PDF, 260 KB

english, 2003

27

Design, Synthesis, and Evaluation of Duocarmycin O -Amino Phenol Prodrugs Subject to Tunable Reductive Activation

Lajiness, James P., Robertson, William M., Dunwiddie, Irene, Broward, Melinda A., Vielhauer, George A., Weir, Scott J., Boger, Dale L.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 987 KB

english, 2010

28

A Unique Class of Duocarmycin and CC-1065 Analogues Subject to Reductive Activation

Jin, Wei, Trzupek, John D., Rayl, Thomas J., Broward, Melinda A., Vielhauer, George A., Weir, Scott J., Hwang, Inkyu, Boger, Dale L.

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 215 KB

english, 2007

29

Luminescent properties of Gd 2 SiO 5 powder doped with Eu 3+ under VUV–UV excitation

Chen, Yonghu, Liu, Bo, Shi, Chaoshu, Kirm, Marco, True, Marcus, Vielhauer, Sebastian, Zimmerer, Georg

Journal:

Journal of Physics Condensed Matter

Year:

2005

Language:

english

File:

PDF, 265 KB

english, 2005

30

Expression of the C-C Chemokine Receptor 7 Mediates Metastasis of Breast Cancer to the Lymph Nodes in Mice

Cunningham, Heather D., Shannon, Laura A., Calloway, Psachal A., Fassold, Brian C., Dunwiddie, Irene, Vielhauer, George, Zhang, Ming, Vines, Charlotte M.

Journal:

Translational Oncology

Year:

2010

Language:

english

File:

PDF, 511 KB

english, 2010

31

Engineering an Antibiotic to Fight Cancer: Optimization of the Novobiocin Scaffold to Produce Anti-proliferative Agents

Zhao, Huiping, Donnelly, Alison C., Kusuma, Bhaskar R., Brandt, Gary E. L., Brown, Douglas, Rajewski, Roger A., Vielhauer, George, Holzbeierlein, Jeffrey, Cohen, Mark S., Blagg, Brian S. J.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.71 MB

english, 2011

32

Prostaglandin E 2 Selectively Antagonizes Prostaglandin F 2α -stimulated T-cell Factor/β-Catenin Signaling Pathway by the FP B Prostanoid Receptor

Fujino, Hiromichi, Vielhauer, George A., Regan, John W.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 690 KB

english, 2004

33

Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells

Shawna B. Matthews, George A. Vielhauer, Craig A. Manthe, Vamsee K. Chaguturu, Kristen Szabla, Robert L. Matts, Alison C. Donnelly, Brian S. J. Blagg, Jeffrey M. Holzbeierlein

Journal:

Year:

2010

Language:

english

File:

PDF, 363 KB

english, 2010

34

The Growth of Malignant Keratinocytes Depends on Signaling Through the PGE2 Receptor EP11

Thompson, Eric J., Gupta, Ashok, Vielhauer, George A., Regan, John W., Bowden, G. Tim

Journal:

Year:

2001

Language:

english

File:

PDF, 641 KB

english, 2001

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